Natural allelic variation of the AZI1 gene controls root growth under zinc-limiting condition
| Autor: | Bouain, Nadia, Satbhai, Santosh B., Korte, Arthur, Saenchai, Chorpet, Desbrosses, Guilhem, Berthomieu, Pierre, Busch, Wolfgang, Rouached, Hatem |
|---|---|
| Přispěvatelé: | Biochimie et Physiologie Moléculaire des Plantes (BPMP), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Gregor Mendel Institute, Austrian Academy of Sciences (OeAW), Vienna Biocenter, Salk Institute for Biological Studies, Plant Molecular and Cellular Biology Laboratory, Evolutionary Genomics Center for Computational and Theoretical Biology (CCTB), Julius-Maximilians-Universität Würzburg [Wurtzbourg, Allemagne] (JMU), European Project: 609398,EC:FP7:PEOPLE,FP7-PEOPLE-2013-COFUND,AGREENSKILLSPLUS(2014), Université de Montpellier (UM)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Julius-Maximilians-Universität Würzburg (JMU) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
lcsh:QH426-470
growth Arabidopsis Gene Expression Plant Science Brassica Research and Analysis Methods Genes Plant Plant Roots Model Organisms Plant and Algal Models Genome-Wide Association Studies Genetics [SDV.BV]Life Sciences [q-bio]/Vegetal Biology Plant Defenses Dicarboxylic Acids development Alleles développement Plant Growth and Development Arabidopsis Proteins rice arabidopsis thaliana zinc Organisms Biology and Life Sciences Eukaryota Computational Biology Genetic Variation Human Genetics Genomics Plants Genome Analysis croissance Chemistry lcsh:Genetics croissance racinaire Root Growth Experimental Organism Systems Seedlings Genetic Loci oryza Plant Physiology Physical Sciences immunité Research Article Developmental Biology Chemical Elements Signal Transduction |
| Zdroj: | PLoS Genetics PLoS Genetics, Public Library of Science, 2018, 14 (4), pp.e1007304. ⟨10.1371/journal.pgen.1007304⟩ PLoS Genetics, Vol 14, Iss 4, p e1007304 (2018) PLoS Genetics, 2018, 14 (4), pp.e1007304. ⟨10.1371/journal.pgen.1007304⟩ |
| ISSN: | 1553-7390 1553-7404 |
| DOI: | 10.1371/journal.pgen.1007304⟩ |
| Popis: | Zinc is an essential micronutrient for all living organisms and is involved in a plethora of processes including growth and development, and immunity. However, it is unknown if there is a common genetic and molecular basis underlying multiple facets of zinc function. Here we used natural variation in Arabidopsis thaliana to study the role of zinc in regulating growth. We identify allelic variation of the systemic immunity gene AZI1 as a key for determining root growth responses to low zinc conditions. We further demonstrate that this gene is important for modulating primary root length depending on the zinc and defence status. Finally, we show that the interaction of the immunity signal azelaic acid and zinc level to regulate root growth is conserved in rice. This work demonstrates that there is a common genetic and molecular basis for multiple zinc dependent processes and that nutrient cues can determine the balance of growth and immune responses in plants. Author summary Plants have evolved mechanisms to cope with complex environments in which resources as well as potential threats are fluctuating. Thereby, plants modulate their growth based on multiple cues from the environment. In this study, by exploring natural genetic variation in Arabidopsis to study the role of zinc in regulating primary root length, we find a major locus governing this is the AZELAIC ACID INDUCED (AZI1) locus, previously known to be involved in systemic acquired resistance. We then showed that regulatory variation at AZI1 contributes significantly to this natural variation. Importantly, the known AZI1 function led us to show that there is an interaction of zinc deficiency and the defence pathway. While the studies of the roles of the defence signal AzA and AZI1 had been restricted to the aboveground tissues, we clearly showed an important role of this pathway in the root, which is zinc-dependant. Our observations regarding the interaction of zinc and AzA-dependent defence pathways on root growth are not a fluke of evolution, but they are evolutionary conserved between dicots and monocots. Taken together, these results will serve as a basis to design new strategies for improvement agricultural crop species able to modulate growth and defence. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|