An attempt of identifying MS-associated loci as a follow-up of a genomic linkage study in the Italian population

Autor:	D Alfonso, S., Lorenza Nisticò, Bocchio, D., Bomprezzi, R., Marrosu, M. G., Murru, M. R., Lai, M., Massacesi, L., Ballerini, C., Repice, A., Salvetti, M., Montesperelli, C., Ristori, G., Trojano, M., Liguori, M., Gambi, D., Quattrone, A., Tosi, R., Momigliano-Richiardi, P.
Rok vydání:	2000
Předmět:	Family Health Multiple Sclerosis Genetic Linkage Histocompatibility Testing association study candidate regions italian families microsatellites multiple sclerosis HLA-DR Antigens Italy Humans Chromosomes Human Pair 19 Alleles Follow-Up Studies HLA-DRB1 Chains Microsatellite Repeats
Zdroj:	Scopus-Elsevier Europe PubMed Central
ISSN:	1355-0284
Popis:	Subsequent to a genomic linkage study on Sardinian and Continental Italian families, we considered the possibility that some of the tested microsatellite markers showed association to MS. Markers selected on the basis of the data obtained in the original set of 70 multiplex families were tested for MS association in an additional set of 154 simplex families. A limited set of markers were further tested on an additional set of 100 simplex families. The results indicate the presence of a putative MS gene in 19q13.13.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5fa9c02396237218fc2834600591afd3 https://pubmed.ncbi.nlm.nih.gov/10871779 Zobrazit plný text záznamu