Sonographic ventriculography: a new potential use for sonographic contrast agents in neonatal hydrocephalus
| Autor: | Ga, Taylor, Janet Soul, Ps, Dunning |
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| Rok vydání: | 1999 |
| Předmět: | |
| Zdroj: | AJNR Am J Neuroradiol Europe PubMed Central |
| ISSN: | 0195-6108 |
| Popis: | BACKGROUND AND PURPOSE: Sonographic identification of communicating and noncommunicating forms of posthemorrhagic hydrocephalus can be difficult. This study evaluates the feasibility of using sonographic contrast agents to determine ventricular patency in a newborn animal model. METHODS: A craniotomy was performed and a catheter was placed under sonographic guidance into the lateral ventricle in five anesthetized newborn piglets. Sonograms were obtained before and after intraventricular injection of 0.01 mL of a sonographic contrast agent (Imagent, formulation AF0150; Alliance Pharmaceutical Corp, San Diego, CA) diluted in 1 mL normal saline, and images were assessed for presence and location of echogenic contrast material. RESULTS: Flow of contrast material was identifiable from the ipsilateral lateral ventricle into the contralateral lateral ventricle, and through the third and fourth ventricles into the basal cisterns during real-time sonography in every animal. Ventricular and cistern echogenicity remained increased for approximately 4 minutes after injection. CONCLUSION: Contrast-enhanced sonographic ventriculography has the potential to identify patency of CSF pathways in newborns with hydrocephalus and an indwelling ventricular catheter. |
| Databáze: | OpenAIRE |
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