[The challenges of preventing mother-to-child transmission of HIV in Africa]

Autor: Becquet , Renaud, Leroy , Valériane
Přispěvatelé: Epidémiologie, santé publique et développement, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale ( INSERM ) -IFR99-ISPED, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR99-ISPED, Becquet, Renaud
Jazyk: francouzština
Rok vydání: 2007
Předmět:
Time Factors
MESH: Infant Formula
MESH : HIV
HIV Infections
MESH : Pregnancy Trimester
Third
MESH: Africa
MESH : Randomized Controlled Trials as Topic
MESH: Pregnancy
Pregnancy
Risk Factors
MESH: Risk Factors
Infant Mortality
MESH: Infant Mortality
MESH : Female
Pregnancy Complications
Infectious
Randomized Controlled Trials as Topic
MESH: Drug Resistance
Viral
MESH: HIV
Postpartum Period
MESH: Infant
Newborn
MESH : Infant
[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie
MESH: HIV Infections
MESH : Adult
MESH: Infant
MESH : Risk Factors
Infant Formula
MESH : Postpartum Period
MESH : Drug Resistance
Viral
Breast Feeding
Anti-Retroviral Agents
MESH: Breast Feeding
MESH: Pregnancy Trimester
Third
Drug Therapy
Combination
Female
MESH : Time Factors
Adult
MESH : Africa
Pregnancy Trimester
Third
Health Promotion
MESH : Infant
Newborn
MESH: Anti-Retroviral Agents
MESH: Postpartum Period
Drug Resistance
Viral
MESH : HIV Infections
Humans
MESH : Anti-Retroviral Agents
MESH: Pregnancy Complications
Infectious
MESH : Infant Mortality
MESH: Humans
MESH : Drug Therapy
Combination
MESH: Time Factors
MESH : Humans
Infant
Newborn
HIV
Infant
MESH: Adult
MESH : Disease Transmission
Vertical
Infectious Disease Transmission
Vertical
MESH: Drug Therapy
Combination
MESH : Pregnancy
MESH: Randomized Controlled Trials as Topic
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
MESH : Pregnancy Complications
Infectious
Africa
MESH : Health Promotion
MESH : Infant Formula
MESH : Breast Feeding
MESH: Health Promotion
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
MESH: Female
MESH: Disease Transmission
Vertical
Zdroj: La Presse Médicale
La Presse Médicale, Elsevier Masson, 2007, 36 (12 Pt 3), pp.1947-57. 〈10.1016/j.lpm.2007.02.031〉
La Presse Médicale, Elsevier Masson, 2007, 36 (12 Pt 3), pp.1947-57. ⟨10.1016/j.lpm.2007.02.031⟩
ISSN: 0755-4982
2213-0276
DOI: 10.1016/j.lpm.2007.02.031〉
Popis: International audience; HIV (human immunodeficiency virus) is the leading cause of infant mortality in Africa where 1700 children are infected each day, principally by mother-to-child transmission. Prevention of this risk is therefore a public health priority. Considerable progress has been made in the past 10 years in preventing the risk of mother-to-child transmission in the peripartum period in Africa: short antiretroviral regimens during the third trimester of pregnancy can reduce transmission rates to less than 5%. Breast-feeding, which is widespread and prolonged in Africa, causes many HIV infections and thus reduces the efficacy of peripartum interventions. Interventions that offer alternatives to prolonged breast-feeding and are both socially acceptable and safe for the infant can effectively reduce the risk of postnatal HIV transmission. But operational implementation of these postnatal interventions remains complex. Use of antiretroviral agents as prophylaxis for mother and child during the breast-feeding period and clinical management of breast-feeding mothers with combined antiretroviral treatments offer hope that the risk of postnatal HIV transmission can be reduced, but the effectiveness and safety of these interventions still need to be assessed.
Databáze: OpenAIRE
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