Complex interactions in soil-transmitted helminth co-infections from a cross-sectional study in Sri Lanka
| Autor: | Lepper, H, Prada, J, Davis, E, Gunawardena, S, Hollingsworth, T |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Ancylostomatoidea Male Ascaris lumbricoides/growth & development Adolescent Necator americanus Helminthiasis Hookworm Infections Soil Young Adult co-infection 1108 Medical Microbiology Tropical Medicine Helminths parasitic diseases Prevalence Gastrointestinal Tract/parasitology Animals Humans Trichuriasis Ascaris lumbricoides Child Trichuris trichiura Trichuriasis/complications Sri Lanka Ascariasis Life Cycle Stages Coinfection Trichuris/growth & development Ascariasis/complications Hookworm Infections/complications Original Articles Ancylostomatoidea/growth & development Gastrointestinal Tract Cross-Sectional Studies Trichuris 1117 Public Health And Health Services Child Preschool Helminths/growth & development Female epidemiology 0605 Microbiology |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene Lepper, H C, Prada, J M, Davis, E L, Gunawardena, S A & Hollingsworth, T D 2018, ' Complex interactions in soil-transmitted helminth co-infections from a cross-sectional study in Sri Lanka ', Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 112, no. 8, pp. 397-404 . https://doi.org/10.1093/trstmh/try068 |
| ISSN: | 1878-3503 0035-9203 |
| DOI: | 10.1093/trstmh/try068 |
| Popis: | BACKGROUND: Co-infection with multiple soil-transmitted helminth (STH) species is common in communities with a high STH prevalence. The life histories of STH species share important characteristics, particularly in the gut, and there is the potential for interaction, but evidence on whether interactions may be facilitating or antagonistic are limited.METHODS: Data from a pretreatment cross-sectional survey of STH egg deposition in a tea plantation community in Sri Lanka were analysed to evaluate patterns of co-infection and changes in egg deposition.RESULTS: There were positive associations between Trichuris trichiura (whipworm) and both Necator americanus (hookworm) and Ascaris lumbricoides (roundworm), but N. americanus and Ascaris were not associated. N. americanus and Ascaris infections had lower egg depositions when they were in single infections than when they were co-infecting. There was no clear evidence of a similar effect of co-infection in Trichuris egg deposition.CONCLUSIONS: Associations in prevalence and egg deposition in STH species may vary, possibly indicating that effects of co-infection are species dependent. We suggest that between-species interactions that differ by species could explain these results, but further research in different populations is needed to support this theory. |
| Databáze: | OpenAIRE |
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