Vineland adaptive behavior scales to identify neurodevelopmental problems in children with Congenital Hyperinsulinism (CHI)
| Autor: | Salomon Estebanez, Maria, Mohamed, Zainab, Michaelidou, Maria, Collins, Hannah, Rigby, Lindsey, Skae, Mars, Padidela, Raja, Rust, Stewart, Dunne, Mark, Cosgrove, Karen, Banerjee, Indraneel, Nicholson, Jacqueline |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Adolescent Developmental delay Research Vineland Developmental Disabilities lcsh:R Neurodevelopment Age Factors lcsh:Medicine Development cognitive assessment Cohort Studies Glucose Cognitive assessment Sex Factors Neurodevelopmental Disorders Child Preschool Surveys and Questionnaires Adaptation Psychological Insulin Humans Congenital Hyperinsulinism Female Child |
| Zdroj: | Orphanet Journal of Rare Diseases Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-10 (2017) Salomon Estebanez, M, Mohamed, Z, Michaelidou, M, Collins, H, Rigby, L, Skae, M, Padidela, R, Rust, S, Dunne, M, Cosgrove, K, Banerjee, I & Nicholson, J 2017, ' Vineland Adaptive Behavior Scales to identify neurodevelopmental problems in children with Congenital Hyperinsulinism (CHI) ', Orphanet Journal of Rare Diseases, vol. 12, no. 96 . https://doi.org/10.1186/s13023-017-0648-7 |
| ISSN: | 1750-1172 |
| DOI: | 10.1186/s13023-017-0648-7 |
| Popis: | Background Congenital Hyperinsulinism (CHI) is a disease of severe hypoglycaemia caused by excess insulin secretion and associated with adverse neurodevelopment in a third of children. The Vineland Adaptive Behavior Scales Second Edition (VABS-II) is a parent report measure of adaptive functioning that could be used as a developmental screening tool in patients with CHI. We have investigated the performance of VABS-II as a screening tool to identify developmental delay in a relatively large cohort of children with CHI. VABS-II questionnaires testing communication, daily living skills, social skills, motor skills and behaviour domains were completed by parents of 64 children with CHI, presenting both in the early neonatal period (Early-CHI, n = 48) and later in infancy (Late-CHI, n = 16). Individual and adaptive composite (Total) domain scores were converted to standard deviation scores (SDS). VABS-II scores were tested for correlation with objective developmental assessment reported separately by developmental paediatricians, clinical and educational psychologists. VABS-II scores were also investigated for correlation with the timing of hypoglycaemia, gender and phenotype of CHI. Results Median (range) total VABS-II SDS was low in CHI [-0.48 (-3.60, 4.00)] with scores |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|