Prevalence of factors related to vascular calcifications in patients with chronic kidney disease on dialysis
| Autor: | Guillermo Rosa-Diez, Griselda Bratti, Graciela Filannino, Adriana Peñalba, Fabián Otreras, Miriam Ledesma, Martín Ortemberg, Gustavo Laham, Mariana Vásquez-Durand, Soledad Crucelegui, Mariano Forrester, Carlos Musso, Marcelo Orias, Ricardo Heguilen, Carlos Díaz, Ricardo García-Mónaco, Oscar Velan, Hernán Trimarchi |
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| Rok vydání: | 2017 |
| Předmět: |
lcsh:Immunologic diseases. Allergy
Male Kauppila Adragao lcsh:R Argentina lcsh:Medicine Middle Aged lcsh:Infectious and parasitic diseases Radiography Cross-Sectional Studies Cardiovascular Diseases Echocardiography Renal Dialysis Risk Factors cardiovascular system Prevalence dialysis Humans lcsh:RC109-216 Renal Insufficiency Chronic lcsh:RC581-607 Vascular Calcification chronic kidney disease |
| Zdroj: | Medicina (Buenos Aires), Vol 77, Iss 3, Pp 207-213 (2017) |
| ISSN: | 0025-7680 |
| Popis: | The main aim of the study was to determine the prevalence of vascular calcifications in patients with chronic kidney disease on dialysis in our population assessed by X-ray. The secondary objectives were to determine the cardiovascular risk factors associated with the presence of vascular calcifications and to evaluate the complementary use of the echocardiogram in a cross-sectional, observational, multicentric study. We included patients with chronic kidney disease on dialysis, age =18 years with at least 3 months of renal replacement therapy in 8 dialysis centres in Argentina. The degree of vascular calcification was determined using Adragao and Kauppila scores. The presence of valvular calcifications was established through a trans-thoracic doppler echocardiogram. Univariate and multivariate analysis were undertaken, considering the degree of vascular calcification as the dependent variable; 443 adult patients were evaluated at 8 centres across 5 provinces in Argentina. The prevalence of vascular calcifications by the X-rays was 63%, while 73% presented calcifications in hands and pelvis, with an Adragao score > 3, and 60% presented calcifications in the abdominal aorta with a Kauppila score > 4. The prevalence of valvular calcifications: 28%. We have shown a higher rate of vascular calcifications with the use of plain X-rays when compared to the prevalence of valvular calcifications obtained with echocardiograms. In this regard, valvular calcifications were present particularly in those patients with a severe level of radiological vascular calcification |
| Databáze: | OpenAIRE |
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