Persistence of infectious hepatitis A virus and its genome in artificial seawater
| Autor: | Arnal, R, Crance, C, Gantzer, C., Schwartzbrod, S, Deloince, R., Billaudel, S |
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| Přispěvatelé: | GANTZER, Christophe, Centre hospitalier universitaire de Nantes (CHU Nantes), Institut de biologie et chimie des protéines [Lyon] (IBCP), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 1998 |
| Předmět: |
[SDV.EE]Life Sciences [q-bio]/Ecology
environment [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology Reverse Transcriptase Polymerase Chain Reaction viruses fungi virus diseases Genome Viral biochemical phenomena metabolism and nutrition digestive system diseases Cell Line [SDV.EE] Life Sciences [q-bio]/Ecology environment [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Humans Seawater Hepatovirus |
| Zdroj: | Zentralblatt fur Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine Zentralblatt fur Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine, 1998, pp.279-84 |
| ISSN: | 0934-8859 |
| Popis: | International audience; The stability of the hepatitis A virus (HAV) genome detectable by RT-PCR in artificial sterile seawater seeded with HAV has been compared to that of HAV detectable in cell culture. The HAV genome was detectable by RT-PCR for 232 days while virus particles were detectable in cell culture for only 35 days. This difference in stability indicates that detection of the HAV genome by RT-PCR is not a reliable indicator of the survival of HAV detectable in cell cultures. However, before these results can be extrapolated to stability in natural seawater, the effect of additional elements in the natural environment, such as bacteria, fungi and suspended matter, on the stability of the HAV genome and cell culture infectious HAV particles, will have to be examined. |
| Databáze: | OpenAIRE |
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