Healing of fresh tibial fractures with OP-1. A preliminary report

Autor:	Maniscalco, P., FABRIZIO RIVERA, Gambera, D., Crainz, E., Bertone, C., Urgelli, S.
Rok vydání:	2002
Předmět:	Adult Male External Fixators Bone Morphogenetic Protein 7 Recombinant Fusion Proteins Middle Aged Combined Modality Therapy Tibial Fractures Treatment Outcome Fracture Fixation Transforming Growth Factor beta Bone Morphogenetic Proteins Humans Female Fractures Closed Aged
Zdroj:	Europe PubMed Central Scopus-Elsevier
ISSN:	0392-4203
Popis:	Osteogenic proteins (OP) are elements of a class of natural growth factors called Bone Morphogenetic Proteins (BMP). A specific member of this class is OP-1, a human recombinant protein that has osteogenic properties. The osteoinductive and osteoconductive properties of OP-1, with its specific collagen matrix, promote the generation of new functionally active, biologically and biomechanically mature bone. We carried out a clinical study to verify the potential of this protein in fresh tibial closed fractures, using OP-1 associated with osteosynthesis by means of a monolateral external fixator.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::466678b246d03235b08f6d57ac4aba29 https://pubmed.ncbi.nlm.nih.gov/12233274 Zobrazit plný text záznamu