Use of Basiliximab with the Standard Immunosuppressive Protocol in Pediatric Renal Transplantation: A Double-Blind Randomized Clinical Trial

Autor: Shemshadi, M., Hoseini, R., Zareh, R., Otukesh, H.
Rok vydání: 2020
Předmět:
Zdroj: Int J Organ Transplant Med
ISSN: 2008-6482
Popis: BACKGROUND: Several randomized clinical trials performed on adult renal transplant recipients have shown a significant reduction in the incidence of acute rejection by using basiliximab as induction therapy. However, few studies have been conducted on kidney graft survival following the use of the drug among pediatric transplant recipients. OBJECTIVE: To address the efficacy and safety of basiliximab in the improvement of the survival of children with kidney transplants. METHODS: This randomized, double-blind single-center clinical trial was conducted on 28 children (57% male) who underwent live-unrelated renal transplantation. They were randomly assigned into an intervention group receiving basiliximab (10 mg in patients weighing
Databáze: OpenAIRE