Specific IgA to lactic acid bacteria in feces of children consuming milk fermented by yoghurt symbiosis and Lactobacillus casei (Danone strain DN 114 001)

Autor:	Faure, G. C., Morisset, M., Gobert, B., Guerin, C., Pedone, C., Bouley, C., Bene, M. C.
Přispěvatelé:	Service d'Immunologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Danone Research, Groupe DANONE
Rok vydání:	2002
Předmět:	food and beverages Infant Yogurt Streptomyces [SDV.MP.PRB.LAC]Life Sciences [q-bio]/Microbiology and Parasitology/domain_sdv.mp.prb/domain_sdv.mp.prb.lac Immunoglobulin A Feces Lactobacillus Lacticaseibacillus casei Milk Child Preschool Fermentation Animals Humans France
Zdroj:	Advances in Experimental Medical Biology Advances in Experimental Medical Biology, 2001
ISSN:	0065-2598
Popis:	An immunoreactive role of lactic acid bacteria established in animals has seldom been investigated in humans. In a large-scale clinical study, children from day-care centers received either yoghurt (Y), milk fermented by yoghurt symbiosis and Lactobacillus casei (DN 114 001) (YC), or gelified milk (GM) as diet supplements during two 30-day supplementation periods separated by one 30-day period without supplementation. Feces samples were collected before, during, and after the 2nd supplementation period. Proteins were extracted in a buffer containing enzymatic inhibitors. IgA levels were assessed and adjusted to the weight of feces samples. Specific IgA to lactic acid bacteria strains (Streptococcus thermophilus 8901A, 8902A; Lactobacillus bulgaricus; Lactobacillus casei) present in Y and YC were assayed in ELISA and adjusted to individual IgA levels. Mean levels of fecal IgA were within reported ranges for pediatric populations of similar age. IgA levels decreased significantly but transiently in children receiving Y, and increased significantly in children receiving GM, but did not vary in the group of children who were given YC. Specific IgA to the 4 strains tested increased significantly during the supplementation period only in the group of children receiving GM, while it was transient and not significant in children receiving YC. No variation was noted in children given Y Specific IgA to lactic acid bacteria can be assayed in feces. Supplementation with fermented milks might induce a mucosal tolerance to environmental flora.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::42fff0549fdb85dcc04ad207d60863ec https://pubmed.ncbi.nlm.nih.gov/11787706 Zobrazit plný text záznamu