Multiple Intravitreal Liposomal Amphotericin B for a Case of Candida glabrata Endophthalmitis

Autor:	Sakai, Daiki, Imai, Hisanori, Nakamura, Makoto
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Ophthalmology ocular candidiasis candida endophthalmitis fungal endophthalmitis intravitreal injection Case Report liposomal amphotericin b RE1-994 bacterial infections and mycoses
Zdroj:	Case Reports in Ophthalmology, Vol 12, Iss 2, Pp 485-491 (2021) Case Reports in Ophthalmology
ISSN:	1663-2699
Popis:	We report a case of Candida glabrata endophthalmitis which was effectively treated by intravitreal liposomal amphotericin B (L-AMB) injection. A 72-year-old man was referred to our department for positive blood culture of Candida glabrata. First ophthalmologic examination revealed a chorioretinal lesion in left eye, and the patient was diagnosed as possible candida chorioretinitis. Despite systemic antifungal therapy, his chorioretinal lesion increased in both eyes and complicated by vitritis. Intravitreal administration of L-AMB was introduced for probable candida endophthalmitis. Finally, improvement of vitritis and regression of chorioretinal lesions were obtained by total of 9 times intravitreal injection. Our case suggests the safety and efficacy of intravitreal L-AMB injection for Candida glabrata endophthalmitis.
Databáze:	OpenAIRE
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