[Hypersensitivity pneumonitis related to Penicillium chrysogenum and mesophilic Streptomyces: the usefulness of the Medical Indoor Environment Councelor (MIEC)]
| Autor: | A, Tiotiu, C, Metz-Favre, G, Reboux, R, Kessler, F, de Blay |
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| Přispěvatelé: | Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Service de Pneumologie, Nouvel Hôpital Civil Strasbourg, Département des Maladies Respiratoires (STRASBOURG - Pneumo), CHU Strasbourg, Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre National de la Recherche Scientifique ( CNRS ), Département des Maladies Respiratoires ( STRASBOURG - Pneumo ) |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Counseling
Male MESH: Smoking MESH : Male MESH : Penicillium chrysogenum MESH : Alveolitis Extrinsic Allergic MESH: Streptomyces MESH: Alveolitis Extrinsic Allergic Penicillium chrysogenum [ SDV.EE.SANT ] Life Sciences [q-bio]/Ecology environment/Health Humans MESH : Middle Aged [SDV.EE.SANT]Life Sciences [q-bio]/Ecology environment/Health MESH : Streptomyces MESH: Humans MESH: Middle Aged MESH: Counseling Smoking MESH : Humans Middle Aged MESH: Radiography Thoracic MESH : Radiography Thoracic Streptomyces MESH: Male MESH : Counseling MESH : Smoking MESH : Air Pollution Indoor Air Pollution Indoor Radiography Thoracic MESH: Air Pollution Indoor MESH: Penicillium chrysogenum Alveolitis Extrinsic Allergic |
| Zdroj: | Revue de Pneumologie Clinique Revue de Pneumologie Clinique, Elsevier Masson, 2013, 69 (5), pp.278-82 |
| ISSN: | 0761-8417 |
| Popis: | International audience; Hypersensitivity pneumonitis (HP) occurred after organic antigens inhalation at home is rare and the diagnosis is very often difficult. We report the case of a 55-year male patient with allergic asthma since childhood, well controlled with inhaled corticosteroids, twice hospitalized for respiratory distresses. The patient presented fever (39°C), dry cough, rapidly progressive dyspnea, chest pain and crackles. Blood gas analysis found a hypoxemia of 52 mmHg, and CT-scan showed ground glass images in the upper lobes. Respiratory function tests showed severe obstructive syndrome and a decrease of diffusion test. HP was suspected because the symptoms were triggered by domestic environmental. The Medical Indoor Environment Councelor (MIEC) visited the patient's house and camper and performed air and dust samples. Moldy walnuts were found in the camper. The identification of microorganisms present in the air and on the surfaces in the camper was used for serum precipitins research by double diffusion (DD) and electrosyneresis (E) methods. From the 14 antigens tested, serological tests were considered significant for mesophilic Streptomyces (five arcs DD, six arcs E) and Penicillium chrysogenum (one arc DD, four arcs E). After removal from the camper of the objects suspected to be contaminated, the patient's symptoms regressed. This is a typical case of domestic HP to mesophilic Streptomyces and P. chrysogenum. The MIEC's intervention was useful in both diagnosis and treatment. |
| Databáze: | OpenAIRE |
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