Recent Advances in Brain Physiology and Cognitive Processing****

Autor: Pereira Junior, Alfredo [UNESP], Pereira, Maria Alice Ornellas [UNESP], Furlan, Fábio Augusto
Přispěvatelé: Universidade Estadual Paulista (Unesp), Universidade de Marília (UNIMAR)
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Mens Sana Monographs
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
ISSN: 1998-4014
0973-1229
Popis: Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:25:27Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:31:05Z : No. of bitstreams: 1 2-s2.0-79955115529.pdf: 812394 bytes, checksum: cfb793639c4706e9ce04ad6490610ad9 (MD5) Made available in DSpace on 2014-05-27T11:25:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-01-01 The discovery of participation of astrocytes as active elements in glutamatergic tripartite synapses (composed by functional units of two neurons and one astrocyte) has led to the construction of models of cognitive functioning in the human brain, focusing on associative learning, sensory integration, conscious processing and memory formation/retrieval. We have modelled human cognitive functions by means of an ensemble of functional units (tripartite synapses) connected by gap junctions that link distributed astrocytes, allowing the formation of intra- and intercellular calcium waves that putatively mediate large-scale cognitive information processing. The model contains a diagram of molecular mechanisms present in tripartite synapses and contributes to explain the physiological bases of cognitive functions. It can be potentially expanded to explain emotional functions and psychiatric phenomena. © MSM 2011. Department of Philosophy of Science Campus Rubião Jr. State University of São Paulo (UNESP), 18618-000, Botucatu-SP Department of Psychiatric Nursing Faculty of Medicine State University of São Paulo (UNESP), Botucatu-SP Department of Physiology Faculty of Medicine and Nursing University of Marília, Marília-SP Department of Philosophy of Science Campus Rubião Jr. State University of São Paulo (UNESP), 18618-000, Botucatu-SP Department of Psychiatric Nursing Faculty of Medicine State University of São Paulo (UNESP), Botucatu-SP
Databáze: OpenAIRE
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