Impact of PET/CT among patients with suspected mycotic aortic aneurysms

Autor: Husmann, Lars, Huellner, Martin W, Gruenig, Hannes, Eberhard, Nadia, Mestres, Carlos A, Rancic, Zoran, Hasse, Barbara
Přispěvatelé: University of Zurich
Rok vydání: 2021
Předmět:
Male
Lymphoma
Pulmonology
Cancer Treatment
Vascular Medicine
Diagnostic Radiology
10234 Clinic for Infectious Diseases
Hematologic Cancers and Related Disorders
Positron Emission Tomography Computed Tomography
Medicine and Health Sciences
Prospective Studies
Tomography
Immune Response
Aged
80 and over
Antimicrobials
Radiology and Imaging
Disease Management
Drugs
Hematology
Middle Aged
Aortic Aneurysm
Oncology
11548 Clinic for Vascular Surgery
Medicine
Radiographic Image Interpretation
Computer-Assisted
Female
Aneurysms
Research Article
Imaging Techniques
Science
Immunology
610 Medicine & health
Neuroimaging
Research and Analysis Methods
Sensitivity and Specificity
Microbiology
Signs and Symptoms
Fluorodeoxyglucose F18
Diagnostic Medicine
Microbial Control
Humans
Vascular Diseases
Aged
Pharmacology
Inflammation
Cancers and Neoplasms
Biology and Life Sciences
10181 Clinic for Nuclear Medicine
Pneumonia
Radiopharmaceuticals
Clinical Medicine
Aneurysm
Infected
Positron Emission Tomography
Neuroscience
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258702 (2021)
ISSN: 1932-6203
Popis: PurposeTo determine the impact of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) on clinical management in patients with suspected mycotic aortic aneurysms (MAA).Materials and methodsFor this observational cohort study 101 PET/CT were acquired in 50 patients, thereof 50 for the initial diagnosis/baseline scan, 51 for follow-up. Impact on patient management was defined in three categories: PET/CT results were "confirmed" (by clinical follow-up), "suspected" (conclusive, not confirmed), or "misleading" (proven wrong by follow-up). For clinical follow-up patient data were recorded at the time of imaging, and at the latest recorded clinical visit. It included patient demographics, clinical information, laboratory data, results of microbiology and other diagnostic procedures, information about treatment, and patient's general health condition.ResultsIn four patients (8%) no clinical follow-up was feasible, the other 46 patients were clinically followed for a median of 898 days (IQR 320-4105). The combined evaluation of all 101 PET/CT demonstrated an impact on patient management in 78,5% of cases (48,5% confirmed, 30% suspected). Results of 21,5% of the PET/CT examinations were misleading. Respective values at baseline and at follow-up were: impact on patient management in 82% and 74,5% (70% and 27.5% confirmed, and 12% and 47% suspected), misleading cases in 18% and 25.5%.ConclusionIn MAA, PET/CT has a high impact on patient management, which is more pronounced with baseline than with follow-up examinations. However, PET/CT results may be misleading in a smaller proportion of cases.
Databáze: OpenAIRE
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