Self-reported alcohol consumption and its association with adherence and outcome of antiretroviral therapy in the Swiss HIV Cohort Study
| Autor: | Conen, A, Fehr, J, Glass, T R, Furrer, H, Weber, R, Vernazza, P, Hirschel, B, Cavassini, M, Bernasconi, E, Bucher, H C, Battegay, M |
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| Přispěvatelé: | University of Zurich, Battegay, M |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Questionnaires Alcohol Drinking HIV Infections/ drug therapy 610 Medicine & health HIV Infections 2725 Infectious Diseases Middle Aged Medication Adherence 10234 Clinic for Infectious Diseases Cohort Studies 3004 Pharmacology Cross-Sectional Studies Switzerland/epidemiology Risk Factors Surveys and Questionnaires Prevalence 2736 Pharmacology (medical) Humans ddc:576.5 Female Switzerland Alcohol Drinking/ adverse effects/ epidemiology |
| Zdroj: | Antiviral Therapy, Vol. 14, No 3 (2009) pp. 349-357 |
| ISSN: | 1359-6535 |
| Popis: | BACKGROUND: Alcohol consumption leading to morbidity and mortality affects HIV-infected individuals. Here, we aimed to study self-reported alcohol consumption and to determine its association with adherence to antiretroviral therapy (ART) and HIV surrogate markers. METHODS: Cross-sectional data on daily alcohol consumption from August 2005 to August 2007 were analysed and categorized according to the World Health Organization definition (light, moderate or severe health risk). Multivariate logistic regression models and Pearson's chi(2) statistics were used to test the influence of alcohol use on endpoints. RESULTS: Of 6,323 individuals, 52.3% consumed alcohol less than once a week in the past 6 months. Alcohol intake was deemed light in 39.9%, moderate in 5.0% and severe in 2.8%. Higher alcohol consumption was significantly associated with older age, less education, injection drug use, being in a drug maintenance programme, psychiatric treatment, hepatitis C virus coinfection and with a longer time since diagnosis of HIV. Lower alcohol consumption was found in males, non-Caucasians, individuals currently on ART and those with more ART experience. In patients on ART (n=4,519), missed doses and alcohol consumption were positively correlated (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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