[Ischemic heart disease and metabolic syndrome X (family study)]
| Autor: | Gi, Lifshits, Nikolaev KIu, Ea, Oteva, Aa, Nikolaeva |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Adolescent Arteriosclerosis Body Weight Cholesterol HDL Hypercholesterolemia Myocardial Infarction Myocardial Ischemia Cholesterol LDL Middle Aged Autonomic Nervous System Diseases Risk Factors Hyperinsulinism Hypertension Humans Triiodothyronine Female Insulin Resistance Triglycerides Apolipoproteins B |
| Zdroj: | Europe PubMed Central Konstantin Nikolaev |
| ISSN: | 0040-3660 |
| Popis: | To evaluate prevalence of metabolic syndrome "X" (MS) components in the families of probands and their wives regarding the presence of hyperinsulinemia and in probands' children of both sexes regarding their having vegetovascular dystonia.92 families were selected by the proband who survived acute myocardial infarction (MI) at the age under 50: 92 probands (mean age 47 +/- 1.1 years), 57 probands' wives (mean age 47 +/- 0.7 years), 20 sons (mean age 18.3 +/- 0.8 years), 24 daughters (mean age 19.1 +/- 1.0 years). Two groups were formed: group 1 of 48 probands and 25 wives (the presence of hyperinsulinemia in the proband); group 2 of 44 probands and 32 their wives (controls with normal insulin levels). Anthropometric, arterial pressure and lipid-hormonal measurements were made by standard techniques. Nutrition was studied by random reproduction of 24-h diet.More factors of risk to develop atherosclerosis and MS"X" components in probands and their wives were found in group 1. More frequent in the parents were the following MS components: hypoalphacholesterolemia, overweight, arterial hypertension, hyperapolipoprotein-B-emia. Vegetovascular asthenia in the probands' children predisposed to cardiovascular diseases is closely linked with the presence of hypoalphacholesterolemia, hypertriglyceridemia, overweight and arterial hypertension.MS "X" for probands and their wives is a "malignant" risk factor for cardiovascular diseases; in the presence of IHD in father, vegetovascular asthenia in children is a risk factor of cardiovascular disease. |
| Databáze: | OpenAIRE |
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