Clinical Application of the COPD Assessment Test: Longitudinal Data From the COPD History Assessment in Spain (CHAIN) Cohort
| Autor: | Juan P, de Torres, Jose M, Marin, Cristina, Martinez-Gonzalez, Pilar, de Lucas-Ramos, Isabel, Mir-Viladrich, Borja, Cosio, German, Peces-Barba, Miryam, Calle-Rubio, Ingrid, Solanes-García, Ramón, Agüero Balbin, Alfredo, de Diego-Damia, Nuria, Feu-Collado, Inmaculada, Alfageme Michavila, Rosa, Irigaray, Eva, Balcells, Antònia, Llunell Casanovas, Juan Bautista, Galdiz Iturri, Margarita, Marín Royo, Juan J, Soler-Cataluña, Jose Luis, Lopez-Campos, Joan B, Soriano, Ciro, Casanova |
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| Rok vydání: | 2014 |
| Předmět: |
Exercise Tolerance
Time Factors Health Status adult article clinical assessment Prognosis cohort analysis Risk Assessment Severity of Illness Index Pulmonary Disease Chronic Obstructive aged 6 min walk distance age Spain BODE index Exercise Test controlled study Prospective Studies Morbidity Charlson Comorbidity Index cardiopulmonary exercise test chronic obstructive lung disease Follow-Up Studies |
| Zdroj: | Repositori Universitat Jaume I Universitat Jaume I CHEST r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname |
| ISSN: | 0012-3692 |
| Popis: | OBJECTIVE: The COPD Assessment Test (CAT) has been proposed for assessing health status in COPD, but little is known about its longitudinal changes. The objective of this study was to evaluate 1-year CAT variability in patients with stable COPD and to relate its variations to changes in other disease markers. METHODS: We evaluated the following variables in smokers with and without COPD at baseline and aft er 1 year: CAT score, age, sex, smoking status, pack-year history, BMI, modified Medical Research Council (mMRC) scale, 6-min walk distance (6MWD), lung function, BODE (BMI, obstruction, dyspnea, exercise capacity) index, hospital admissions, Hospital and Depression Scale, and the Charlson comorbidity index. In patients with COPD, we explored the association of CAT scores and 1-year changes in the studied parameters. R ESULTS: A total of 824 smokers with COPD and 126 without COPD were evaluated at baseline and 441 smokers with COPD and 66 without COPD 1 year later. At 1 year, CAT scores for patients with COPD were similar ( ± 4 points) in 56%, higher in 27%, and lower in 17%. Of note, mMRC scale scores were similar ( ± 1 point) in 46% of patients, worse in 36%, and better in 18% at 1 year. One-year CAT changes were best predicted by changes in mMRC scale scores ( β -coefficient, 0.47; P |
| Databáze: | OpenAIRE |
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