In vitro fertilization is associated with placental accelerated villous maturation

Autor: Londero, Ambrogio P, Orsaria, Maria, Parisi, Nadia, Tassi, Alice, Pittini, Carla, Driul, Lorenza, Mariuzzi, Laura
Rok vydání: 2021
Předmět:
Zdroj: Int J Clin Exp Pathol
ISSN: 1936-2625
Popis: Objective: Accelerated placental maturation is regarded as a sign of vascular malperfusion and is often interpreted as a compensatory response by the placenta. In vitro embryo culture affects placental development. This study assessed placental maturation in spontaneous conceived and in vitro conceived pregnancies. Methods: Retrospective cohort study on a single center between 2014 and 2017. For this study, preterm placentas of singleton pregnancies between 24 and 36 weeks were considered. Routine placental examinations were retrospectively reviewed. Results: During the considered period, 423 placentas of singleton pregnancies were assessed. Three hundred ninety-six placentas were from spontaneous conception and 20 from in vitro fertilization and embryo transfer (IVF/ET). IVF/ET was significantly associated with accelerated villous maturation (AVM) and distal villous hypoplasia (DVH) (P
Databáze: OpenAIRE