Neurological disorders and inflammatory bowel diseases
| Autor: | Casella, Giovanni, Tontini, Gian Eugenio, Bassotti, Gabrio, Pastorelli, Luca, Villanacci, Vincenzo, Spina, Luisa, Baldini, Vittorio, Vecchi, Maurizio |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Crohn’s disease
Extraintestinal manifestations Demyelinating neuropathies Cerebrovascular diseases Inflammatory Bowel Diseases digestive system diseases Multiple sclerosis Progressive multifocal encephalopathy Inflammatory bowel diseases Neurological disorders Side effects Ulcerative colitis Animals Cerebrovascular Disorders Gastrointestinal Agents Humans Immunosuppressive Agents Nervous System Diseases Risk Factors Topic Highlight |
| Popis: | Extraintestinal manifestations occur in about one-third of patients living with inflammatory bowel disease (IBD) and may precede the onset of gastrointestinal symptoms by many years. Neurologic disorders associated with IBD are not frequent, being reported in 3% of patients, but they often represent an important cause of morbidity and a relevant diagnostic issue. In addition, the increasing use of immunosuppressant and biological therapies for IBD may also play a pivotal role in the development of neurological disorders of different type and pathogenesis. Hence, we provide a complete and profound review of the main features of neurological complications associated with IBD, with particular reference to those related to drugs and with a specific focus on their clinical presentation and possible pathophysiological mechanisms. |
| Databáze: | OpenAIRE |
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