Leukocytes in the glomerular capillary lumen in Masugi nephritis. A scanning electron microscopic study of freeze-cracked specimens

Autor:	Makino, Hirofumi, Takaoka, Michio, Komoda, Keizo, Tokuyama, Kiyoyuki, Ota, Zensuke, Ofuji, Tadashi, Kaneshige, Tetsuji
Rok vydání:	1981
Předmět:	Masugi nephritis Male leukocyte Nephritis urogenital system Kidney Glomerulus Rats Inbred Strains Basement Membrane Rats Leukocytes Microscopy Electron Scanning Animals Freeze Fracturing Rabbits scanning electron microscopy
Zdroj:	Acta medica Okayama. 35(5)
ISSN:	0386-300X
Popis:	Masugi nephritis was induced in rats by a single intravenous injection of rabbit anti-rat kidney serum, and studied with a scanning electron microscope. A characteristic finding was the presence of white cells, probably polymorphonuclear leukocytes, with many microspikes which penetrated through degenerated glomerular endothelial cells to be in direct contact with the glomerular basement membrane. This finding confirms the pathogenic role of leukocytes in glomerulonephritis induced by anti-glomerular basement membrane antibody.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2b9b77817f78a023b3d304b5dbfa1d8a https://pubmed.ncbi.nlm.nih.gov/6459000 Zobrazit plný text záznamu