Ventricular ejection force in growth-retarded fetuses
Autor: | G, Rizzo, A, Capponi, D, Rinaldo, D, Arduini, C, Romanini |
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Jazyk: | angličtina |
Rok vydání: | 1995 |
Předmět: |
Left
Gestational Age Ultrasonography Prenatal Ventricular Function Left Fetal Heart Pregnancy Humans Prenatal Ventricular Function Comparative Study human fetus heart Non-U.S. Gov't pathophysiology Ultrasonography Fetal Growth Retardation article Doppler echography methodology Stroke Volume case control study intrauterine growth retardation Echocardiography Doppler Doppler echocardiography Right female heart right ventricle function Echocardiography comparative study gestational age heart left ventricle function heart stroke volume physiology pregnancy Case-Control Studies Female Human Support Non-U.S. Gov't Ventricular Function Right Settore MED/40 - Ginecologia e Ostetricia Support |
Popis: | The objective of this study was to determine whether in growth-retarded fetuses secondary to uteroplacental insufficiency the cardiac ventricles exert a force different from that of appropriately grown fetuses. Doppler echocardiographic studies were performed in 156 appropriately grown fetuses (gestational age 18-38 weeks) and in 72 growth-retarded fetuses (gestational age 24-36 weeks) free from structural and chromosomal abnormalities and characterized by Doppler changes in the umbilical artery and middle cerebral artery suggesting uteroplacental insufficiency as the most likely etiology of the growth defect. Right and left ventricular ejection force values were calculated from velocity waveforms recorded at the level of aortic and pulmonary valves, according to Newton's second law of motion. In appropriately grown fetuses, left and right ventricular ejection force values significantly increased with advancing gestation and the two ventricles exerted similar force. In growth-retarded fetuses, the ventricular ejection force was significantly and symmetrically decreased in both ventricles. Among growth-retarded fetuses, a poorer perinatal outcome was observed in those fetuses in which the ejection force of both ventricles was below the 5th centile of the normal limits for gestation. In 12 growth-retarded fetuses followed longitudinally during the last week preceding intrauterine death or Cesarean section due to antepartum heart-rate late decelerations, a significant decrease of ejection force was found in both ventricles. Finally, a significant relationship was found between the severity of acidosis and right and left ventricular ejection force values in 22 fetuses in which Doppler recordings were performed immediately before cordocentesis.(ABSTRACT TRUNCATED AT 250 WORDS) |
Databáze: | OpenAIRE |
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