Disruption of posteromedial large-scale neural communication predicts recovery from coma

Autor:	Stein, Silva, Francesco, de Pasquale, Corine, Vuillaume, Beatrice, Riu, Isabelle, Loubinoux, Thomas, Geeraerts, Thierry, Seguin, Vincent, Bounes, Olivier, Fourcade, Jean-Francois, Demonet, Patrice, Péran
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	Adult Male Consciousness Recovery of Function Middle Aged Aged Brain Injuries/diagnosis Brain Injuries/epidemiology Coma/diagnosis Coma/epidemiology Consciousness/physiology Female Glasgow Coma Scale Gyrus Cinguli/metabolism Humans Magnetic Resonance Imaging/methods Nerve Net/metabolism Parietal Lobe/metabolism Predictive Value of Tests Recovery of Function/physiology Gyrus Cinguli Magnetic Resonance Imaging Article Brain Injuries Parietal Lobe Coma Nerve Net
Zdroj:	Neurology, vol. 85, no. 23, pp. 2036-2044 Neurology
Popis:	OBJECTIVE: We hypothesize that the major consciousness deficit observed in coma is due to the breakdown of long-range neuronal communication supported by precuneus and posterior cingulate cortex (PCC), and that prognosis depends on a specific connectivity pattern in these networks. METHODS: We compared 27 prospectively recruited comatose patients who had severe brain injury (Glasgow Coma Scale score
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::27ae269cd1fbc38dca3703526a72edae https://serval.unil.ch/notice/serval:BIB_7C0991CD7EF4 Zobrazit plný text záznamu