Acute hippocampal damage as a prognostic biomarker for cognitive decline but not for epileptogenesis after experimental traumatic brain injury

Autor: Eppu, Manninen, Karthik, Chary, Riccardo, De Feo, Elina, Hämäläinen, Pedro, Andrade, Tomi, Paananen, Alejandra, Sierra, Jussi, Tohka, Olli, Gröhn, Asla, Pitkänen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Popis: It is necessary to develop reliable biomarkers for epileptogenesis and cognitive impairment after traumatic brain injury when searching for novel antiepileptogenic and cognition-enhancing treatments. We hypothesized that a multiparametric magnetic resonance imaging (MRI) analysis along the septotemporal hippocampal axis could predict the development of post-traumatic epilepsy and cognitive impairment. We performed quantitative T
Databáze: OpenAIRE