Skin Metastasis of Hypopharyngeal Carcinoma to the Nasal Tip

Autor: Shindo, Masahisa, Yoshida, Yuichi, Tominaga, Kyoko, Yamamoto, Osamu
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Yonago Acta medica. 2013, 56(2), 57?58
Popis: Head and neck squamous cell carcinoma (SCC) rarely metastasizes to the skin. Metastases to the nasal tip from hypopharyngeal malignancies are extremely rare. We present a patient with nasal tip metastasis from hypopharyngeal SCC. A 74-year-old man with hypopharyngeal and esophageal carcinomas had a red nodule on his nasal tip (so-called "clown nose"). Histopathologically, atypical squamoid cell nests had proliferated in a lobular fashion from the dermis to subcutaneous tissue. Those atypical cells were identical to primary tumor cells in the hypopharynx. Based on these findings, a diagnosis of skin metastasis from hypopharyngeal SCC was made. In patients with malignant disease, biopsy should be performed for any suspicious skin lesion. In a patient like ours, "clown nose" might be a symptom of cutaneous metastasis. When clinicians note a "clown nose", they should consider malignancies in the neck and chest areas.
Databáze: OpenAIRE