Transport through liquid membranes containing omeprazole and lansoprazole
| Autor: | An, Nagappa, Pv, Pandi, Pk, Mishra, Rk, Girish, Shanmukh I |
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| Rok vydání: | 2012 |
| Předmět: |
Ions
Chemistry Pharmaceutical Molecular Conformation Membranes Artificial Hydrogen-Ion Concentration Biochemistry Models Biological 2-Pyridinylmethylsulfinylbenzimidazoles Permeability Bicarbonates Cholesterol Chlorides Models Chemical Cations Drug Design Lecithins Lansoprazole Enzyme Inhibitors Omeprazole |
| Zdroj: | Europe PubMed Central |
| ISSN: | 0301-1208 |
| Popis: | Omeprazole and lansoprazole, the therapeutically important drugs belonging to proton pump inhibitor category are extensively used in the treatment of gastric ulcers. Transport through liquid membranes generated by these drugs in lecithin-cholesterol mixture in series with a supporting membrane has been studied. The data obtained show the formation of liquid membrane in series with the supporting membrane. Transport of cations, chloride and bicarbonate ions in the presence liquid membranes generated by omeprazole and lanzoprazole indicate the modification in the permeability of various permeants. |
| Databáze: | OpenAIRE |
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