| Autor: |
Thomas D., Gaspar D., Sorushanova A., Milcovich G., Spanoudes K., Mullen A. M., O'Brien T., Pandit A., Zeugolis D. I. |
| Přispěvatelé: |
Thomas D., Gaspar D., Sorushanova A., Milcovich G., Spanoudes K., Mullen A.M., O'Brien T., Pandit A., Zeugolis D.I. |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Biotechnology and bioengineering. 113(6) |
| ISSN: |
1097-0290 |
| Popis: |
Self-assembly in tissue engineering refers to the spontaneous chemical or biological association of components to form a distinct functional construct, reminiscent of native tissue. Such self-assembled systems have been widely used to develop platforms for the delivery of therapeutic and/or bioactive molecules and various cell populations. Tissue morphology and functional characteristics have been recapitulated in several self-assembled constructs, designed to incorporate stimuli responsiveness and controlled architecture through spatial confinement or field manipulation. In parallel, owing to substantial functional properties, scaffold-free cell-assembled devices have aided in the development of functional neotissues for various clinical targets. Herein, we discuss recent advancements and future aspirations in scaffold and scaffold-free self-assembled devices for regenerative medicine purposes. Biotechnol. Bioeng. 2016;113: 1155-1163. © 2015 Wiley Periodicals, Inc. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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