[Interferon-specific cellular receptors in cultured human cells, differing in sensitivity to alpha-interferon]

Autor:	An, Narovlianskiĭ, Am, Amchenkova, Si, Borukhov, Eg, Alimov, Alex Strongin, Khesin IaE
Předmět:	Interferon Type I Humans Interferons Receptors Immunologic Cells Cultured Recombinant Proteins Receptors Interferon
Zdroj:	Europe PubMed Central
Popis:	The interferon-specific cellular receptors in human cells cultures differing in sensitivity to alpha-interferon have been studied. The J-41 cells resistant to alpha-interferon are practically devoid of receptors highly specific to alpha-interferon. The coefficient of equilibrium and the number of receptors analyzed after Scatchard for J-96 culture of cells are 15.6 x 10(11) M-1 and 210 +/- 90, respectively. Evidently, resistance of J-41 cells to alpha-interferon is connected with the absence of interferon receptors and, as a consequence, inability to interferon-receptor interaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1ed48835db3680ab0cad191566edd01d http://europepmc.org/abstract/med/2478879 Zobrazit plný text záznamu