Remission and employment status in schizophrenia and other psychoses : One-year prospective study in Croatian patients treated with risperidone long acting injection

Autor: Mihaljevic-Peles, A., Sagud, M., Ivona Šimunović Filipčić, Grosic, V., Pedisic, I., Emsley, R.
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Psychiatria Danubina
Volume 28
Issue 3
Scopus-Elsevier
ISSN: 0353-5053
Popis: Background: While numerous studies have confirmed the efficacy of risperidone long-acting injectable (RLAI) on many clinical outcomes in patients with schizophrenia, there is no data regarding its influence on employment status. Subject and methods: This was a 12-month observational study with flexible doses of RLAI on a Croatian population of patients with schizophrenia and other psychoses. Visits were at baseline and after 1, 3, 6 and 12 months of treatment. Treatment response was evaluated using Clinical Global Impression of Illness Severity (CGI-S) and Improvement (CGI-I) scales, while remission was defined by 8 items of Positive and Negative Syndrome Scale (PANSS). Employment status was determined at baseline and at study endpoint. Results: A total of 362 patients were included, with a median age of 37 (interquartile range 29- 47) years, 63.5 % were males and 67.4% were hospitalised at baseline. Overall 258 (71.3%) patients completed the study. Improvements in CGI-S scores from baseline were significant (p
Databáze: OpenAIRE