[Estimation of activity of bis-netropsin derivatives based on a model of an experimental cutaneous herpes simplex virus disease of guinea pigs]

Autor:	Vl, Andronova, Sl, Grokhovskiĭ, An, Surovaia, Gv, Gurskiĭ, Pg, Deriabin, Vov Dk, L., Georgy Galegov
Předmět:	Male Ointments Disease Models Animal Administration Topical Guinea Pigs Acyclovir Animals Herpes Simplex Netropsin Herpesvirus 1 Human Antiviral Agents
Zdroj:	Europe PubMed Central
Popis:	Using the model of an experimental cutaneous infection of guinea pig males caused by herpes simple virus type 1, it is shown that application of dimerico derivatives of netropsin Lys-bis Nt and 15Lys-bis Nt in the form of polietilenglicol-based ointment suppresses viral infection more effectively than acyclovir.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1afac7f164baad06d440930713de7aca http://europepmc.org/abstract/med/23785759 Zobrazit plný text záznamu