| Autor: |
Ml, Wiesel, Jy, Borg, Grunebaum L, marc vasse, Levesque H, Bierme R, Sie P |
| Jazyk: |
francouzština |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Europe PubMed Central |
| ISSN: |
0755-4982 |
| Popis: |
Protein S is the cofactor of activated protein C which, together with the antithrombin system, is a major regulator of coagulation. Congenital protein S deficiency is an important risk factor for venous thrombosis. In this study of 105 patients with protein S deficiency, 64 had one of several thromboembolic accidents, including 14 arterial thrombotic accidents involving the central nervous system or the myocardium. These accidents occurred in young subjects (mean age: 25 +/- 13 years) only one-third of whom had another risk factor. This high frequency of arterial thrombosis associated with protein S deficiency calls for a prospective study in young subject with cerebral vascular accident or myocardial infarction. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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