Temperature changes during and after eccentric contractions and its effect on force and desmin loss in rat

Autor:	Vasaghi-Gharamaleki, B., Keshavarz, M., Gharibzadeh, S., Sotodeh, M., Marvi, H., Mosayebnejad, J., ismail ebrahimi
Předmět:	Male lcsh:R5-920 Temperature Isolated Perfused Muscle macromolecular substances Rats Desmin Rats Sprague-Dawley Eccentric Contraction Animals Isometric Force Loss sense organs lcsh:Medicine (General) Muscle Contraction
Zdroj:	Scopus-Elsevier Acta Medica Iranica, Vol 49, Iss 4, Pp 225-232 (2011) Acta Medica Iranica, Vol 49, Iss 4 (2011)
Popis:	The typical features of eccentric exercise-induced muscle damage is prolonged loss of muscle strength and the most rapid structural change in the fibers is loss of immunostaining for the intermediate filament protein, desmin. In this study isolated perfused rat muscle was used to examine the direct effect of temperature changes on the eccentric contraction-induced force and desmin loss. The left medial gastrocnemius muscle was separated and the entire lower limb was transferred into a prewarmed (35o C) organ bath. Temperature was adjusted to 31 or 39o C during and after eccentric contractions. Maximal isometric force and desmin loss were measured after 15 isometric or eccentric contractions. According to our data, organ bath temperature changes during or after eccentric contractions had no significant effect on force loss. However, a strong correlation between desmin loss and temperature changes during (r = 0.886, P< 0.05) and a weak correlation between desmin loss and temperature changes after (r= 0.699, P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0c3db53fa4e17240a941c26b66244e93 http://www.scopus.com/inward/record.url?eid=2-s2.0-80054695123&partnerID=MN8TOARS Zobrazit plný text záznamu