A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up

Autor: Ryan, B M, Lefort, F, McManus, R, Daly, J, Keeling, P W N, Weir, D G, Kelleher, D
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Popis: Background and aims: Mutant tumour derived DNA has been detected in the sera of colorectal cancer patients. We investigated if mutant serum KRAS2 was detectable preoperatively in a large group of patients with colorectal neoplasia. A prospective study of 94 patients who underwent putative curative resection for colorectal carcinoma (CRC) was performed to ascertain if serum mutant KRAS2 could be used postoperatively as a disease marker.
Databáze: OpenAIRE