Gill endocrine cells in the goldfish Carassius carassius var. auratus and their impairment following experimental lead intoxication

Autor:	Franchini, Antonella, Rebecchi, B., Amb, Fantin
Rok vydání:	1999
Předmět:	Gills Serotonin Carps Time Factors Microvilli Carassius lead intoxication Calcium-Binding Proteins Neuropeptides Epithelial Cells Enkephalins Free Radical Scavengers Cytoplasmic Granules Immunohistochemistry Lead Animals
Zdroj:	The Histochemical journal. 31(8)
ISSN:	0018-2214
Popis:	The presence of endocrine cells in the gills of the goldfish Carassius carassius and the effects of lead intoxication (5 mg l(-1)) on their relative abundance and secretory activity were studied. Endocrine cells synthesizing peptido-like (met and leu-enkephalin and neuropeptide Y) and serotonin-like substances were detected in gill filaments by immunocytochemical procedures. Decreased immunoreactivity for two enkephalins and neuropeptide Y was observed after 48 and 96 h lead exposure. In contrast, increased serotonin immunoreactivity was evident after a one-week treatment. A search for Ca++-binding proteins was also carried out by immunocytochemical methods. Calbindin D-28K and S-100-like molecules were detected in gill epithelium, and their expression appeared enhanced after lead exposure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::091ede40ad602987579bd4f98d59585a https://pubmed.ncbi.nlm.nih.gov/10507463 Zobrazit plný text záznamu Full text from SpringerLink