| Autor: |
del Rey-Moreno A, Valero-López A, Basilio Gómez-Pozo, Mayorga-Mayorga C, Hernández-Quero J, Ml, Garrido-Torres-Puchol, Mj, Torres-Jaén, Lozano-Maldonado J |
| Předmět: |
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| Zdroj: |
Europe PubMed Central |
| Popis: |
Anisakis simplex can be a cause of digestive symptoms. Our aim was to evaluate the epidemiological antecedents and immunological data available for a differentiation between patients with anisakidosis and those with other acute abdominal problems.this is a prospective cohort study involving 134 patients with acute abdominal problems: 52 patients were diagnosed with anisakidosis by means of surgical and pathological findings and/or specific IgE seroconversion against Anisakis simplex (group A), and in 82 patients anisakidosis had been ruled out (group NA: non-anisakidosis). We evaluated the antecedent of raw fish ingestion, the skin prick test, and IgE immunoblotting as diagnostic tools.patients in groups A and NA differ in terms of prior raw fish ingestion (p0.0001) and positive SPT (p0.0001), with their respective negative predictive values (NPV) being 98.39% (95%CI: 90.17-99.92) and 95.56% (95%CI: 83.64-99.23). Regarding immunoblotting, in 86.2% of patients in group A a band of 60 kDa was detected, which was also detected in 19.2% of patients in group NA.a negative answer to the question about raw or undercooked fish ingestion has very high sensitivity and NPV (98.39%), and is thus reasonably reliable to rule out anisakidosis. The absence of cutaneous sensitization to crude A. simplex extract gives a high probability (95.56%) that the illness is absent. The presence of a band of about 60 kDa in immunoblotting would be useful for diagnosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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