| Autor: |
Dominique, Endres, Karl, Bechter, Harald, Prüss, Alkomiet, Hasan, Johann, Steiner, Frank, Leypoldt, Ludger, Tebartz van Elst |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Der Nervenarzt 90(5), 547-563 (2019). doi:10.1007/s00115-019-0700-z |
| DOI: |
10.1007/s00115-019-0700-z |
| Popis: |
According to present concepts, primary psychotic disorders in the schizophrenia spectrum are probably caused by a complex interaction between multigenetic vulnerability and causally relevant environmental factors. In contrast, secondary psychotic disorders are the result of likely identifiable organic factors either in terms of a first causation (etiology) or a secondary cause (pathogenesis). In this context, autoantibody(ab)-associated autoimmune encephalitis (AE) plays an increasingly important role. Within the group of ab-associated AE with neuropsychiatric symptoms, anti-N-methyl-D-aspartate receptor encephalitis is the most prevalent one. Psychopathologically, polymorphic psychotic symptoms are often observed at onset of AE; however, over the course of this condition or even initially other neuropsychiatric phenomena are also common. The ill-defined entity of a steroid-responsive encephalopathy with thyroid antibodies (Hashimoto's encephalitis) is a heterogeneous syndrome that may also comprise isolated psychotic disorders presenting as classical schizophrenia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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