| Autor: |
Thomas K, Villiger, Anaïs, Roulet, Arnaud, Périlleux, Matthieu, Stettler, Hervé, Broly, Massimo, Morbidelli, Miroslav, Soos |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Popis: |
N-linked glycosylation is of key importance for the efficacy of many biotherapeutic proteins such as monoclonal antibodies (mAbs). Media components and cell culture conditions have been shown to significantly affect N-linked glycosylation during the production of glycoproteins using mammalian cell fed-batch cultures. These parameters inevitably change in modern industrial processes with concentrated feed additions and cell densities beyond 2 × 10 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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