Activity of sparfloxacin against Mycobacterium leprae measured by the proportional bactericidal test

Autor:	R D, McDermott-Lancaster, D K, Banerjee
Rok vydání:	1993
Předmět:	Mycobacterium leprae Disease Models Animal Mice Ofloxacin Anti-Infective Agents Leprosy Antitubercular Agents Colony Count Microbial Animals Mice Nude Microbial Sensitivity Tests Quinolones Fluoroquinolones
Zdroj:	International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 61(4)
ISSN:	0148-916X
Popis:	The activity of 25 mg/kg and 50 mg/kg sparfloxacin was measured against Mycobacterium leprae in normal (immunocompetent) mouse foot pads by the proportional bactericidal test. This was compared with the action of 25, 50, and 150 mg/kg ofloxacin by the same method. Sparfloxacin, at both concentrations, was found to be strongly bactericidal by this method, comparable to 150 mg/kg ofloxacin.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ffe226960c855c4441023831be421058 https://pubmed.ncbi.nlm.nih.gov/8151193 Zobrazit plný text záznamu