Anti-neutrophil cytoplasm antibodies in patients with giant cell arteritis and/or polymyalgia rheumatica

Autor:	J M, Berthelot, A, Lamour, D, Mottier, Y L, Pennec, M, Dueymes, J, Jouquan, P, Le Goff, P, Youinou
Rok vydání:	1992
Předmět:	Aged 80 and over Male Giant Cell Arteritis Fluorescent Antibody Technique Enzyme-Linked Immunosorbent Assay Middle Aged Antibodies Antineutrophil Cytoplasmic Polymyalgia Rheumatica Immunoglobulin G Humans Female Aged Autoantibodies Retrospective Studies
Zdroj:	Annales de medecine interne. 143(7)
ISSN:	0003-410X
Popis:	Anti-neutrophil cytoplasm antibodies (ANCA) were detected at low titers by indirect immunofluorescence in 1 out of 13 patients with giant cell arteritis (GCA) alone, 7 out of 30 with polymyalgia rheumatica (PMR) alone and 4 out of 15 with GCA plus PMR (8, 23 and 27%, respectively). Anti-myeloperoxidase antibodies were also demonstrated by an enzyme-linked immunosorbent assay in 4 patients with GCA alone (31%), 13 with PRM alone (42%) and 5 with GCA plus PRM (33%). The C-reactive protein response was significantly higher (p0.05) in ANCA-positive than in ANCA-negative patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ffc761b2e60705084677e4a84c3a733e https://pubmed.ncbi.nlm.nih.gov/1300861 Zobrazit plný text záznamu