Clotest (rapid urease test) in the diagnosis of Helicobacter pylori infection

Autor: T M, Ng, K M, Fock, J, Ho, A L, Tan, S C, Chia, C K, Yap, C N, Chew, E N, Chee
Rok vydání: 1992
Předmět:
Zdroj: Singapore medical journal. 33(6)
ISSN: 0037-5675
Popis: Over a period of 3 months, 85 patients who underwent gastroscopy had antral biopsy taken for Clotest, histology and/or culture for Helicobacter pylori (HP). The sensitivity and specificity of Clotest were found to be 77% and 96% respectively with negative predictive value of 63% and positive predictive value of 98%. Ninety-two percent of the positive Clotests were positive within 20 minutes, thus giving rapid result. Therefore, Clotest is a rapid, sensitive and highly specific test for HP infection. A high correlation between HP infection and chronic gastritis was noted and the prevalence of HP infection in patients with duodenal ulcer (90%) was higher than that of gastric ulcer (64%) or non-ulcer group (65%).
Databáze: OpenAIRE