| Autor: |
M, Palestini, A, Messina, F, Ciaraffo, G M, De Sanctis, G, Errera, S G, Corradini |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques. 12(2) |
| ISSN: |
0392-291X |
| Popis: |
Eleven hemodialysis patients (9 M, 2 F, aged 65 +/- 20 yrs) (Group A) were treated with thymopentin (TP-5) 50 mg as adjuvant therapy to HB vaccination, with 3 weekly administrations, the week before and the two following the first dose of Pasteur vaccine, 5 micrograms. The percentage of patients developing a sufficient antibody titer (20 mUI/ml) after 4 vaccine doses was not statistically different from that obtained among control groups B and C. The age- and sex- matched controls received the same vaccine schedule without adjuvant. The percentages were as follows: Group A 54.5%, Group B 63.6%, Group C 60%. No local or systemic side effects were encountered after the TP-5 administration. The authors suggest that a short TP-5 treatment as an adjuvant therapy to HB vaccination is not effective in patients maintained on hemodialysis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
