High copper and low zinc serum levels in Iranian patients with multiple sclerosis: a case control study

Autor: Ali, Ghazavi, Saeed, Kianbakht, Keyvan, Ghasami, Ghasem, Mosayebi
Rok vydání: 2012
Předmět:
Zdroj: Clinical laboratory. 58(1-2)
ISSN: 1433-6510
Popis: The purpose of this study was to evaluate the levels of zinc (Zn) and copper (Cu) in the serum of Iranian patients with multiple sclerosis (MS).The serum levels of zinc (Zn) and copper (Cu) were measured in sixty Iranian patients with MS and compared with sixty age-, gender- and socioeconomic status-matched healthy subjects without any neurological disorders as controls from the same geographical area.Significantly lower serum Zn and higher serum Cu levels were found in the MS patients compared with the controls (p0.0001 and p = 0.002, respectively). The serum Zn level of the secondary-progressive MS patients was significantly lower compared with the relapsing-remitting MS patients (p = 0.009). There was no significant difference between the serum Cu levels of the two subgroup of MS patients (p = 0.42).The results suggest significant deviations of the Iranian MS patients' serum Zn and Cu levels from the norm.
Databáze: OpenAIRE