| Autor: |
Alejandra, Godino-Gimeno, Elisa, Sánchez, Raúl, Guillot, Ana, Rocha, Anna Rita, Angotzi, Esther, Leal, Josep, Rotllant, José Miguel, Cerdá-Reverter |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Zebrafish. 17(6) |
| ISSN: |
1557-8542 |
| Popis: |
The melanocortin system is a key structure in the regulation of energy balance. Overexpression of inverse agonists, agouti-signaling protein (ASIP), and agouti-related protein (AGRP) results in increased food intake, linear growth, and body weight. ASIP regulates dorsal-ventral pigment polarity through melanocortin 1 receptor (MC1R) and overexpression induces obesity in mice by binding to central MC4R. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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