[Induction of sarcomas by a nontumorigenic type of foreign body and glutaraldehyde]
Autor: | L V, Ol'shevskaia |
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Rok vydání: | 1988 |
Předmět: | |
Zdroj: | Biulleten' eksperimental'noi biologii i meditsiny. 106(9) |
ISSN: | 0365-9615 |
Popis: | Nontumorigenic form of cellophane has been implanted subcutaneously into rats, and simultaneously an injection of 0.5 ml 2.5% buffered glutaraldehyde has been given at the site of implantation. Glutaraldehyde injections at the same site were repeated at 4 consecutive days. This treatment induced sarcomas in 21 out of 33 rats (63.6%). Mean latency period of tumor development was 15.7 months. Tumours were diagnosed as polymorphocellular, undifferentiated sarcomas, fibrosarcomas. |
Databáze: | OpenAIRE |
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