The importance of loop length on the stability of i-motif structures† †Electronic supplementary information (ESI) available: Experimental details, UV melting curves at 295 nm, and CD spectra at pH 5 and 8. See DOI: 10.1039/c4cc07279k Click here for additional data file

Autor:	Gurung, Sarah P., Schwarz, Christine, Hall, James P., Cardin, Christine J., Brazier, John A.
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	Chemistry Quantitative Biology::Molecular Networks Circular Dichroism Temperature Spectrophotometry Ultraviolet DNA Hydrogen-Ion Concentration Nucleotide Motifs Quantitative Biology::Genomics
Zdroj:	Chemical Communications (Cambridge, England)
ISSN:	1364-548X 1359-7345
Popis:	I-motif stability is enhanced by short loop lengths compared to long loop lengths. Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ff18f8b26c4773f59ed73c3770773a30 http://europepmc.org/articles/PMC4384421 Zobrazit plný text záznamu