Genetic controls of Tas1r3-independent sucrose consumption in mice

Autor:	Cailu, Lin, Michael G, Tordoff, Xia, Li, Natalia P, Bosak, Masashi, Inoue, Yutaka, Ishiwatari, Longhui, Chen, Gary K, Beauchamp, Alexander A, Bachmanov, Danielle R, Reed
Rok vydání:	2020
Předmět:	Sucrose Genotype Quantitative Trait Loci Chromosome Mapping Epistasis Genetic Receptors G-Protein-Coupled Mice Mice Congenic Quantitative Trait Heritable Gene Expression Regulation Species Specificity Animals Carbohydrate Metabolism Alleles Crosses Genetic Genetic Association Studies
Zdroj:	Mammalian genome : official journal of the International Mammalian Genome Society. 32(2)
ISSN:	1432-1777
Popis:	We have previously used crosses between C57BL/6ByJ (B6) and 129P3/J (129) inbred strains to map a quantitative trait locus (QTL) on mouse chromosome (Chr) 4 that affects behavioral and neural responses to sucrose. We have named it the sucrose consumption QTL 2 (Scon2), and shown that it corresponds to the Tas1r3 gene, which encodes a sweet taste receptor subunit TAS1R3. To discover other sucrose consumption QTLs, we have intercrossed B6 inbred and 129.B6-Tas1r3 congenic mice to produce F
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fedfd85af3eef96656af250cba388d36 https://pubmed.ncbi.nlm.nih.gov/33710367 Zobrazit plný text záznamu Full text from SpringerLink