Sobralene, a new sex-aggregation pheromone and likely shunt metabolite of the taxadiene synthase cascade, produced by a member of the sand fly

Autor:	Matthew J, Palframan, Krishna K, Bandi, James G C, Hamilton, Gerald, Pattenden
Rok vydání:	2018
Předmět:	Taxadiene synthase Lutzomyia longipalpis Verticillenes Sand fly Insect pheromone Article ComputingMethodologies_COMPUTERGRAPHICS
Zdroj:	Tetrahedron Letters
ISSN:	0040-4039
Popis:	Graphical abstract Highlights • Established the structure of a diterpenoid sex-aggregation pheromone (sobralene). • Sobralene has a novel bicyclic ring, related to the verticillenes. • Propose sobralene has its origins as a shunt metabolite of taxadiene synthase. A new sex-aggregation pheromone, sobralene, produced by the sand fly Lutzomyia longipalpis from Sobral (Ceará State, Brazil) is shown to have the novel 6,12-membered ring-fused diterpene structure 3. It is proposed that sobralene is a likely shunt metabolite of the taxadiene synthase-catalysed cyclisation of geranygeranyl diphosphate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fec7698070f2d52431397523c8de21db https://pubmed.ncbi.nlm.nih.gov/29780183 Zobrazit plný text záznamu Full Text from ScienceDirect