| Autor: |
Mansi, Bhatt, Varsha, Jamale, Mohan, Kale, Asma A, Hussain, Balkrishna P, Nikam |
| Rok vydání: |
2022 |
| Zdroj: |
Journal of cutaneous and aesthetic surgery. 15(3) |
| ISSN: |
0974-2077 |
| Popis: |
Atrophic acne scarring is an unpleasant and often permanent complication and a therapeutic challenge for dermatologists. Platelet-poor plasma (PPP) gel injections are derived from the patient's own blood and used as a "biofiller" for skin rejuvenation.The objective was to study the efficacy and safety profile of PPP gel in atrophic acne scars.Thirty patients with atrophic acne scars were included in the study. Topical anesthesia was applied on the area of interest 45 min prior to the procedure. 20 mL of blood was collected in eight sodium citrate bulbs and centrifuged to get PPP that is coagulated with heat to form gel. This gel (biofiller) was injected in the scarred areas monthly for 6 months. Patients were evaluated using Goodman and Baron Scar (GBS) scale (quantitative and qualitative), Physician Global Assessment, and Visual Analogue Scale (VAS) at each visit. The final visit was after 3 months of the last procedure.The mean value of GBS at the first visit was 28, which reduced to 8.2 at the final visit. The analysis of variance test was applied to the quantitative scale from the baseline visit to the final visit. The F value was 462.55 with aBiofiller is efficacious in improving atrophic acne scars. It is a simple, minimally invasive, cost-effective procedure with no risk of immunogenic reaction. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
