[Monomers containing 2'-o-alkoxymethyl groups as synthons for the synthesis of oligoribonucleotides by the phosphotriester method]

Autor:	A V, Aralov, V N, Klykov, O G, Chakhmakhcheva, V A, Efimov
Rok vydání:	2012
Předmět:	Aldehydes Azides Oligoribonucleotides Molecular Structure Alkynes Ribonucleotides Catalysis Solid-Phase Synthesis Techniques
Zdroj:	Bioorganicheskaia khimiia. 37(5)
ISSN:	0132-3423
Popis:	A general scheme for the synthesis of ribonucleotide monomers containing alkoxymethyl group in 2'-O-position for the solid-phase phosphotriester oligonucleotide synthesis using O-nucleophilic intramolecular catalysis has been developed. In particular, the monomers containing 2'-O-modifying 2-azidoethoxymethyl, propargyloxymethyl, or 3,4-cyclocarbonatebutoxymethyl groups has been prepared.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fe9387f266834ec41763c32f16e9039e https://pubmed.ncbi.nlm.nih.gov/22332361 Zobrazit plný text záznamu