Substrate recognition by vitamin K-dependent carboxylase

Autor:	M M, Ulrich, B A, Soute, L J, van Haarlem, C, Vermeer
Rok vydání:	1987
Předmět:	Calcium-Binding Proteins Osteocalcin Haplorhini Decarboxylation Substrate Specificity Ligases Carbon-Carbon Ligases Liver Species Specificity Animals Humans Cattle Amino Acid Sequence Chickens
Zdroj:	Thrombosis and haemostasis. 57(1)
ISSN:	0340-6245
Popis:	Decarboxylated osteocalcins were prepared and purified from bovine, chicken, human and monkey bones and assayed for their ability to serve as a substrate for vitamin K-dependent carboxylase from bovine liver. Substantial differences were observed, especially between bovine and monkey d-osteocalcin. Since these substrates differ only in their amino acid residues 3 and 4, it seems that these residues play a role in the recognition of a substrate by hepatic carboxylase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fe15a5362310ca591bb49a66b7f57a7d https://pubmed.ncbi.nlm.nih.gov/3109057 Zobrazit plný text záznamu